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News 2012

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Highlights 2012

December 20, 2012 – Season’s Greetings and best wishes for a healthy and prosperous New Year in 2013 from Gilde Healthcare Partners. We look back on an eventful year of successes and a lot of hard work. Click below for our 2012 highlights.

Gilde invests in Pharmaline

December 20, 2012 – Gilde has invested in Pharmaline, based in Oldenzaal the Netherlands. Pharmaline is specialized in large scale pharmaceutical compounding. The company is one of the few Dutch players whose facilities and production processes are structured to comply with the guidelines of the Dutch…

Related to: Pharmaline

Moximed Initiates US Clinical Study with KineSpring® System in Patients with Knee Osteoarthritis

December 11, 2012 – Moximed, Inc. announced today that the KineSpring® System, an implantable medical spring that works by unloading the weight on the diseased knee joint, has been successfully implanted in the first patient enrolled in its US clinical study, SOAR. This prospective, single-arm clinical…

Related to: Moximed

Prosonix Elects Dr Ken Cunningham as Non-executive Chairman

December 5, 2012 – Prosonix (Oxford, UK), a speciality pharmaceutical company developing a portfolio of inhaled respiratory medicines enabled by its unique particle engineering technology, announces the election of Dr Ken Cunningham as Non-executive Chairman. He replaces Dr Jim Philips, who has been…

Related to: Prosonix

Agendia announces discovery of a gene signature that predicts response to a broad range of cancer

November 27, 2012 – Gene expression profile could have utility to predict responses to targeted therapies and chemotherapies in multiple cancer types IRVINE, CA and AMSTERDAM, THE NETHERLANDS - Agendia, an innovative molecular cancer diagnostics company and leader in personalized medicine, today announced…

Related to: Agendia

Definiens appoints Dr. Gerald Möller as chairman of its supervisory board

November 15, 2012 – Munich, Germany – Definiens AG, the leader in image analysis for Digital Pathology, today announced that Dr. Gerald Möller, has joined the company's supervisory board as an independent member and has been appointed chairman. Following the recent financing round led by Gilde Healthcare…

Related to: Definiens

Moximed's Implantable Knee Spring Successfully Reduces Pain and Quickly Returns Normal Function

October 9, 2012 – Clinical Data with the KineSpring® System Released KineSpring System Highlighted at the London Knee Meeting HAYWARD, Calif. & LONDON - KineSpring System Highlighted at the London Knee Meeting. For the millions of patients with mild to moderate knee osteoarthritis (wear), an innovative…

Related to: Moximed

Pieris Achieves First Milestone Payment in Daiichi Sankyo Collaboration to Develop Anticalin®

October 9, 2012 – Freising, Germany – Pieris AG announced today the achievement of the first financial milestone in its discovery and development collaboration with Daiichi Sankyo Company Limited (hereinafter Daiichi Sankyo; headquartered in Chuo Ward, Tokyo, TSE 4568). The milestone recognizes the…

Related to: Pieris Pharmaceuticals Inc.

Ablynx Reports Excellent Interim Results from Phase I/II Study with its Anti-IL-6R Nanobody, ALX-006

October 4, 2012 – 60% of patients in DAS28 remission at week 12 ACR20 score of 80% at week 12 Very encouraging safety profile at all administered doses Rapid onset of activity with some patients achieving remission as early as week 2 GHENT, Belgium — Ablynx [Euronext Brussels: ABLX] today announced…

Related to: Ablynx

Ablynx Collaborates with Merck to Develop Therapeutic Nanobody Candidates

October 2, 2012 – GHENT, Belgium - Ablynx [Euronext Brussels: ABLX] today announced a collaboration with Merck & Co., Inc., through a subsidiary, to develop and commercialise Nanobody® candidates directed towards a voltage gated ion channel with the option to develop and commercialise a Nanobody to…

Related to: Ablynx

Acacia Pharma announces positive results from Phase IIa nausea & vomiting study in cancer patients

October 1, 2012 – Cambridge, UK – Acacia Pharma, a pharmaceutical company specialising in the development of drugs for cancer supportive care, announces positive results from its Phase IIa proof-of-concept study investigating APD403 for the prevention of acute nausea & vomiting in cancer patients receiving…

Related to: Acacia Pharma

Gilde Healthcare III leads EUR 10 million private financing of Definiens AG

October 1, 2012 – Munich, Germany – Definiens AG, the leader in Image Analysis for Digital Pathology, today announced that it has closed a private round of financing of €10 million. The financing was led by Gilde Healthcare Partners. Existing investors including TVM, Cipio and Definiens’ management…

Related to: Definiens

Stepping Stones (her)opent villa Oosterveld in Arnhem

September 21, 2012 – Arnhem/Elden – Villa Oosterveld met 18 kamers is 21 september officieel geopend door de wethouder van Zorg en Welzijn Henk Kok. Villa Oosterveld is weer open. Het voormalige klooster is nu een Stepping Stones Home & Care zorgvilla voor hulpbehoevende en dementerende ouderen die niet…

Related to: Stepping Stones

United Therapeutics Announces Collaboration with Ascendis Pharma to Develop Self-Injectable Treprost

September 20, 2012 – SILVER SPRING, Md. - United Therapeutics Corporation (NASDAQ: UTHR) announced today that it has signed an exclusive agreement with Ascendis Pharma A/S to apply Ascendis Pharma's proprietary TransCon technology platform to United Therapeutics' treprostinil molecule, the active ingredient…

Related to: Acacia Pharma

Ablynx and its Partner Advance NANOBODY Candidate ALX-0751 in Pre-Clinical Development

September 20, 2012 – GHENT, Belgium - Ablynx [Euronext Brussels: ABLX] today announced that they have advanced the Nanobody® candidate ALX-0751, together with Merck Serono, a division of Merck KGaA, Darmstadt, Germany, into pre-clinical development in the field of oncology. This is the second pre-clinical…

Related to: Ablynx

Ablynx's First Inhaled NANOBODY Successfully Complete Phase 1 Study

September 18, 2012 – ALX-0171 has the potential to become a first-in-class therapy   GHENT, Belgium - Ablynx [Euronext Brussels: ABLX] today announced that it has achieved positive results from a Phase I study with the first ever inhaled Nanobody, ALX-0171, a trivalent molecule which has been specifically…

Related to: Ablynx

Gilde Healthcare Partners Leads USD 17 million Private Financing Round of iWalk, Inc.

September 14, 2012 – BEDFORD, Mass – iWalk Inc., the leader in Personal Bionics, announced that it has closed a private equity financing round of $17 million led by Gilde Healthcare Partners. Existing investors, including WFD Ventures, General Catalyst Partners, and Sigma Partners also participated in…

Related to: BionX

Symphogen Grants Exclusive Worldwide License of Phase II Oncology Drug Candidate Sym004 to Merck

September 6, 2012 – COPENHAGEN, DENMARK – Symphogen A/S, a private biopharmaceutical company developing recombinant antibody mixtures, today announced that an exclusive worldwide license agreement was signed with Merck KGaA, Darmstadt, Germany, for Sym004, an investigational antibody mixture targeting…

Related to: Symphogen

UNIQURE obtains recommendation for market approval in Europe of GLYBERA®

July 20, 2012 – Utrecht, The Netherlands – uniQure (Amsterdam, the Netherlands) has received a positive opinion from the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) that recommends marketing authorization of Glybera® (alipogene tiparvovec) as a treatment for…

Related to: uniQure

Conatus Pharmaceuticals - Caspase Inhibitor Enters Clinical Trial in Islet Transplantation as Treatm

July 19, 2012 – SAN DIEGO, CA and EDMONTON, CANADA — Conatus Pharmaceuticals Inc. and the University of Alberta announced today the treatment of the first patient in an investigator-initiated islet cell transplant Phase I/II trial of emricasan (IDN-6556), a pan-caspase inhibitor. The objective of…

Related to: Conatus Pharmaceuticals

Ablynx Announces New Compelling Results on OZORALIZUMAB (ATN-103) in Rheumatoid Arthritis

June 25, 2012 – Additional Phase II data (ACR20 84%; DAS28 remission 38%) demonstrates that ozoralizumab could have an important competitive and differentiated position in the $24 billion TNFa market Data from the open-label study suggest that ozoralizumab enables individualised treatment, a real…

Related to: Ablynx

ProFibrix Enrolls First Patients in Pivotal Phase III Study with Fibrocaps

June 6, 2012 – Leiden, The Netherlands & Seattle – ProFibrix B.V., a leader in the development of innovative bioactive products to stop bleeding (hemostasis), today announced the start of its pivotal Phase III clinical trial with Fibrocaps (FINISH-3) in spine, liver, vascular and soft tissue surgery. FINISH-3…

Related to: ProFibrix

Agendia raises $65 million in a private financing round

May 31, 2012 – Amsterdam, The Netherlands and Irvine, CA – Agendia, an innovative molecular cancer diagnostics company and leader in personalized medicine, today announced that the company has raised USD $65 million in a private round of equity financing. The financing round was led by the Debiopharm…

Related to: Agendia

Acacia Pharma announces excellent Phase II results for APD421 in post-operative nausea & vomiting

May 28, 2012 – Cambridge, UK – Acacia Pharma announces positive results from its Phase II study of APD421, in the prevention of post-operative nausea & vomiting (PONV). The study showed that APD421 significantly reduced the incidence of nausea and vomiting compared to placebo in adult surgical patients…

Related to: Acacia Pharma

Overname zorgvilla in Doorn afgerond

April 10, 2012 – Doorn — De reeds 45 jaar bestaande zorgvilla Nimmerdor Staete op de Julianaweg 47 in Doorn is overgenomen door Stepping Stones Home & Care, bekend in de regio van o.a. Poort van Wijk op de grens tussen Cothen en Wijk bij Duurstede. Niet alleen de eigenaar is veranderd, maar ook de…

Related to: Stepping Stones

Pieris Presents Preclinical Data for PRS-110 c-Met Antagonist Anticalin at the AACR Annual Meeting

April 4, 2012 – — Results Support Differentiating Drug-like Features for Targeted Anti-cancer Drug —   Chicago, Illinois — Pieris AG announced today the presentation of a range of in vitro and in vivo preclinical data for the company’s proprietary c-Met antagonist program, PRS-110, at the American…

Related to: Pieris Pharmaceuticals Inc.

Ablynx Receives Milestone Payment as Novartis Receives IND Approval for a Nanobody in Oncology

April 2, 2012 – GHENT, Belgium - Ablynx [Euronext Brussels: ABLX] today announced that it has received a €400,000 milestone payment from its collaboration with Novartis. The payment was triggered by the approval of an Investigational New Drug (IND) application from the U.S. Food and Drug Administration…

Related to: Ablynx

ProFibrix Achieved All Primary and Secondary Endpoints in US Phase II Study with Fibrocaps™

January 6, 2012 – LEIDEN, The Netherlands & SEATTLE - ProFibrix B.V., a leader in the development of innovative products for hemostasis, announced that its U.S. multicenter Phase II clinical trial with Fibrocaps in spinal, peripheral vascular and general surgery resulted in a highly statistically significant…

Related to: ProFibrix

ProFibrix US Phase II Study with Fibrocaps™ Meets All Primary and Secondary Endpoints

January 5, 2012 – LEIDEN, The Netherlands & SEATTLE - ProFibrix B.V., a leader in the development of innovative products for hemostasis, today announced that its U.S. multicenter Phase II clinical trial with Fibrocaps in spinal, peripheral vascular and general surgery resulted in a highly statistically…

Related to: ProFibrix

Agendia Signs Contract with Blue Shield of California

January 5, 2012 – IRVINE, CA and AMSTERDAM, THE NETHERLANDS – Agendia, an innovative molecular cancer diagnostics company, today announced that the company has signed a contract with Blue Shield of California, making Agendia an in-network provider. The move paves the way for future in-network coverage…

Related to: Agendia

Acacia Pharma Initiates Phase II Study with APD421 in Post-Operative Nausea & Vomiting (PONV)

January 4, 2012 – Cambridge, UK – Acacia Pharma, a pharmaceutical company specialising in the development of drugs for cancer supportive care, announces the initiation of a Phase II study of APD421, in the prevention of post-operative nausea & vomiting (PONV). PONV remains a clinically significant…

Related to: Acacia Pharma

Gilde Healthcare

Gilde Healthcare

Gilde Healthcare is a specialized healthcare investor managing over €1.4 billion ($1.5 billion) across two fund strategies: venture & growth capital and private equity. Gilde Healthcare's venture & growth capital fund invests in health tech and therapeutics. The venture & growth companies are based in Europe and North America. Gilde Healthcare's private equity fund invests in profitable European lower mid-market healthcare companies with a focus on the Benelux and DACH region. The private equity fund targets healthcare providers, suppliers of medical products and service providers in the healthcare market.

Investment Philosophy

Gilde Healthcare invests in fast growing, innovative businesses delivering better care at lower cost.

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