Gilde Healthcare company Shoulder Innovations Announces Closing of $40 Million Series E Equity Financing - Gilde Healthcare

Gilde Healthcare company Shoulder Innovations Announces Closing of $40 Million Series E Equity Financing

March 10, 2025

Shoulder Innovations, a leader in shoulder replacement technology, today announced the closing of a $40 million Series E equity financing round. The financing was led by existing investor U.S. Venture Partners (USVP), with support from additional existing investors including Gilde Healthcare Partners, Gilmartin Capital, and Aperture Venture Partners. New investors Arboretum Ventures and Sectoral Asset Management also participated.

Proceeds from the financing will be used primarily to advance commercialization of the Company’s InSet™ Total Shoulder and Reverse Shoulder Arthroplasty Systems and support new product development, as well as for general corporate purposes.

“Over recent years, we have significantly expanded our product line, strengthened our sales organization, and emerged as a pure-play leader in shoulder arthroplasty,” said Rob Ball, CEO of Shoulder Innovations. “We appreciate the support of our new and existing investors and see this financing as well-timed as we hone our focus on accelerating commercial momentum and advance our mission of enabling best-in-class outcomes for shoulder specialists and their patients.”

“Shoulder Innovations has established compelling clinical credibility with its disruptive and highly differentiated InSet™ technology, and U.S. Venture Partners is pleased to continue supporting the Company by leading this financing round,” said Casey Tansey, General Partner at U.S. Venture Partners. “Looking ahead, we believe Shoulder Innovations is well-positioned to further advance patient outcomes while delivering economic benefits to healthcare practitioners as a leading innovator in the shoulder arthroplasty market.”

About Shoulder Innovations
Shoulder Innovations is a shoulder arthroplasty-focused medical device development company that designs and commercializes innovative products that demonstrate the potential for improved patient care and reduced overall cost to the healthcare system. Leveraging its breakthrough, patented InSet™ glenoid design, Shoulder Innovations developed a shoulder replacement implant system focused on improving outcomes related to the greatest cause of anatomic shoulder replacement failure: glenoid loosening.

The InSet™ technology has been shown in testing to significantly reduce glenoid implant micro-motion and simplifies the surgical technique, potentially reducing complications or increasing implant longevity.

Beyond addressing one of the biggest problems in anatomic shoulder arthroplasty, Shoulder Innovations has also developed the anatomic reverse shoulder system, designed to work with and maximize the available rotator cuff instead of substituting for it. For more information about Shoulder Innovations and the Power of One™ visit www.shoulderinnovations.com.

About Gilde Healthcare
Gilde Healthcare is a transatlantic specialist investment firm managing over €2.6 billion across two fund strategies: Venture&Growth and Private Equity. The Venture&Growth fund of Gilde Healthcare invests in fast growing companies active in digital health, medtech and therapeutics, based in Europe and North America. The Private Equity fund of Gilde Healthcare participates in profitable lower mid-market healthcare companies based in North-Western Europe. For more information, visit the company’s website at www.gildehealthcare.com.

More news

Gilde Gilde Healthcare Portfolio company SpliceBio Initiates Dose-Expansion Portion of Phase 1/2 ASTRA Clinical Trial for SB-007 for Stargardt Disease

First dose-expansion patient successfully received SB-007  SB-007 addresses the root cause of Stargardt disease with the potential to treat patients across all ABCA4 mutations  SB-007 granted FDA Fast Track designation, following previously received Orphan Drug...
January 9, 2026

Gilde Healthcare acquires a majority stake in Physio CKI, a physiotherapy practice group, from Kapital 1852

Gilde Healthcare's private equity fund announces the acquisition of a majority stake in Physio CKI from Kapital 1852. Physio CKI is a fast-growing group of physiotherapy practices headquartered in Cologne. Founder and managing director Chaled...
December 22, 2025

Okami Medical Announces $45 Million Financing and New CEO Appointment to Drive Next Phase of Growth

Okami Medical, a medical technology company pioneering novel vascular embolization solutions, today announced the successful close of an oversubscribed $45M financing led by new investor Gilde Healthcare with participation from existing investors including Vensana Capital and...
November 20, 2025